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Projects

7/29/2013
To estimate the cost-utility of two intravenous biphosphonate treatment strategies to prevent fractures in post-menopausal women with early-stage breast cancer we developed a Markov model.
7/29/2013
This research was part of the 'Organ donation masterplan', which was an initiative by the Dutch Ministry of Health aiming to investigate opportunities to increase the number of organ donors and the availability of transplantable organs.
7/29/2013
For this projecten we have developed a Disease Elimination Life Table Analysis (DELTA) model containing five sub-models representing diabetes related complications
7/29/2013
Do specific factors enhance the likelihood of drug reimbursement? And conversely, are there factors that hamper a drug’s uptake in formularies?
7/29/2013
The aim of this project was to mathematically represent the transmission of bacteria among individuals of all ages in the US population in order to predict the future direct and indirect effects of vaccination in the US.
7/29/2013
This project aimed to assess the cost-effectiveness of high dose branded statin therapy in comparison to a generic statin in lower doses for the secondary prevention of cardiovascular events in patients with Acute Coronary Syndrome (ACS).
7/29/2013
​In this project we aimed to assess the cost-effectiveness of anti-TNF (Tumor Necrosis Factor) alpha therapy (Humira) in combination with methotrexate (MTX) in comparison to MTX only for the treatment of early rheumatoid arthritis.
7/29/2013
Haemophilia patients that develop inhibitors for clotting agents need alternative treatment. Clinical studies report conflicting efficacy levels for various drugs and dosage regimens. We aimed to synthesize the evidence.
7/29/2013
​In the context of an economic evaluation of therapies to prevent cardiovascular events , Pharmerit had previously developed a Markov model for oral antiplatelet therapies.
7/29/2013
​The aim of this project was to obtain an estimate of the burden-of-illness of severe sepsis. The results of the research have been presented at ISPOR, Rotterdam 2002.
1/8/2014
In this unique project we have successfully developed a framework to integrate pharmacokinetic /pharmacodynamics modeling into a health economic patient simulation model.
7/29/2013
The aim of this project was to evaluate the incremental cost-utility of two treatments in the chronic phase of chronic myelogenous leukemia (CML) after failure of first-line imatinib: dasatinib compared to imatinib.
7/29/2013
In this self-funded project, we designed and compared four different methods for meta-modeling in terms of their computation time and accuracy.
7/29/2013
We developed a computer model that simulated disease progression and treatment decisions of individual (virtual) patients in great detail.
7/29/2013
The aim of this project was to predict the utility effect of four medication strategies for lower urinary tract symptoms (LUTS).